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Beilstein J. Org. Chem. 2021, 17, 2832–2839, doi:10.3762/bjoc.17.194
Graphical Abstract
Figure 1: The structures of chloramphenicol (A) and cucurbit[n]urils (B).
Figure 2: (A) CPE and Q[8] structural model diagram, (B) interaction between CPE and Q[8], (C) CPE@Q[8] stack...
Figure 3: UV–vis absorption spectra of CPE with Q[8] in aqueous solution (A) or hydrochloric acid solution (C...
Figure 4: ITC data obtained for the binding of Q[8] with CPE in an aqueous solution at 25 °C.
Figure 5: 1H NMR spectra of CPE, CPE@Q[8] and Q[8] (VD2O/VDCl = 3:2).
Figure 6: IR spectra recorded for Q[8] (a), CPE (b), a physical mixture of Q[8] and CPE (c), and the CPE@Q[8]...
Figure 7: UV absorption intensity of CPE and CPE@Q[8] changes with time in the artificial gastrointestinal ju...
Figure 8: Release curve of CPE and CPE@Q[8] in artificial gastrointestinal juice (pH 1.2, pH 6.8).